This simulation requires GENESIS version 2.2 and kinetikit version 10. Both are included in the compressed file you have downloaded. We have confirmed that our simulation scripts run on Cent Linux OS 4 in Pentium 4 PCs. If you have a problem, please contact at xtomdoi@atr.jp. //////////////////////////////////////////////////////////////// HOW TO RUN DEMOS To extract TanakaNeuron.tar.gz, type tar zxvf TanakaNeuron.tar.gz A new directory has several files named Fig*.g. To run demos, go into the directory and just type genesis Fig7B.g , genesis Fig9A.g , or genesis FigS7.g GENESIS/kinetikit includes model scripts for the simulation, and displays and saves simulation results in 'simresult/Fig*/'. In simresult/Fig*/, there are MALTAB scripts files (*.m) which display the simulation results as in the Neuron paper. Note that simulation results does not inculde noise, so you cannot directly compare the noise-free simulation results to Fig. 8A, 9A-B. To load the model scripts without demos, type genesis TanakaNeuron.g //////////////////////////////////////////////////////////////// Tomoakazu Doi, PhD, ATR Computational Neuroscience Labs, 02 Apr 2007 xtomdoi@atr.jp