Supplemental Table 3: Categories of parameters

 

known

unknown

Form Purkinje cells

From other cells

From reaction in test tubes

From other molecular subtypes

Time constants, t

 

f2, f3

a6, a8,

e1, e4 ,e9

 

a1, a2, a3, a4, b1, b2, b3, b4, b5, b8, b9, c1, c2, c4,

d1, d2, d3, d4, d5, d6,

e2, e5, e7, e10, f1, f4, f5

Dissociation constants, Kd and Michaelis constants, Km

d1, d2, d3, d4, d5,d6

a1, a2, a4,

f1, f2, f3

b4, b5, c1, c2, c4,

e2, e5, e7, e10

b1, b2, b3,

b8, b9

a3, f4 ,f5

Enzyme turnovers, Vmax

 

b10, b11, b12

a7, c5, e3, e6, e8

b7

a5, b6, c3

Initial concentrations, [ ]

[Ca2+]i, IP3R, MgGreen, parvalbumin, calbindin-D28k,

low-affinity buffer,

low-affinity buffer 2

Glu,

mGluR, Gq, IP3, [Ca2+]ER, [Ca2+]ext, calreticulin

PIP2,

IP3 3-kinase,

IP3 5-phosphatase

PLCb4

 

(taken from PLCb1)

SERCA,

PMCA,

Na+/Ca2+